Treatment of relapses of gestational trophoblastic neoplasias

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Treatment of metastatic gestational trophoblastic neoplasia.

Treatment of persistent gestational trophoblastic neoplasia (GTN) has been one of the success stories of modern day chemotherapy; however, occasional patients with metastatic disease still die. A potential difficulty in assessing published studies is that patient groups can be selected for treatment differently according to how risk categories are defined. The involvement of a specialist team f...

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Introduction: Methotrexate as a single agent chemotherapy in most women with low risk gestational trophoblastic neoplasia (GTN) has been associated with high treatment rate. Combination of methotrexate with Vitamin A due to reduced number of chemotherapy regime courses is one of the treatment options for patients with low-risk GTN. Therefore, this study was performed with aim to determine the e...

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Gestational Trophoblastic Disease (GTD) — Symptoms and Treatment

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Gestational Trophoblastic Disease (GTD) — Symptoms and Treatment

Gestational trophoblastic disease is a spectrum of placental disorders ranging from benign molar pregnancies to the neoplastic conditions such as invasive mole and choriocarcinoma. These patients are identified early due to markedly elevated hCG levels and characteristic ultrasound findings. Uterine evacuation is the recommended treatment, while chemotherapy can be reserved for patients with re...

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ژورنال

عنوان ژورنال: Russian Journal of Oncology

سال: 2020

ISSN: 2412-9119,1028-9984

DOI: 10.18821/1028-9984-2020-25-1-9-16